抗流感病毒药物——Oseltamivir研究进展被引量：1

The Progress of Anti - influenza Virus Drug - Oseltamivir

下载PDF

导出

摘要流感是由流感病毒引起的一种急性呼吸道传染病,严重危害人类的健康和生命.根据流感病毒核蛋白(NP)和膜蛋白(MP)的不同,可将流感病毒分为A、B、C三型,A型常以流行的形式出现,B型常造成局部暴发,C型则多散发.

作者张隽王辰

机构地区首都医科大学附属北京朝阳医院

出处《中国临床医学》 2002年第6期752-752,共1页 Chinese Journal of Clinical Medicine

关键词作用机制药效学临床应用不良反应耐药性抗流感病毒药物 OSELTAMIVIR

参考文献3

1Varghese JN, Colman PM. Three - dimensional structure of the neuraminidase of influenza virus A/Tokyo / 3 / 67 at 2.2 A resolution. J Mol boil, 1991,221:473～486.
2Colman PM, Hoyne PA, Lawrence MC. Sequence and structure alignment of paramyxovirus haemagglutinin - neuraminidase with influenza virus neuraminidase. J Virol, 1993, 67:2972 ～2980.
3Wood ND, Aitken M, Sharp S, et al. Tolerability and pharmacokinetics of the influenza neuraminidase inhibitor oseltamivir) following oral administration of the prodrug Ro- 64- 0796(GS4104) to heath male volunteers. 37th ICAAC, 1997, Toronto.

1杜芝芝,沈月毛,李炳钧,许建初.滑桃树果皮的化学成分[J].天然产物研究与开发,2002,14(2):9-10. 被引量：12
2郑晓珂,史社坡,毕跃峰,冯卫生,王继峰,牛建昭.卷柏中一个新木脂素苷的分离与鉴定[J].药学学报,2004,39(9):719-721. 被引量：27
3韩广轩,谷莉,尹建设,程金玲.鸡蛋参化学成分的研究[J].药学实践杂志,2001,19(3):174-175. 被引量：14
4Bruce G. From glucose to aromatics:recent developments in natu- ral products of the shikimic acid pathway[ J]. Tetrahedron, 1978, 34:3353 - 3383.
5Ma Y ,Xu Q P, Sun J N ,et al. Beneficial effects of shikimic acid on focal cerebral schenaia in rats subjected to middle cerebral artery throlnbosis [ J ]. Acta Pharnmcologica Sinica, 1999,20,701 - 706.
6Morlmoto M. Method for producing highly pure shikimic acid [ P]. J172002080421,2002.
7Sasaki S,Shimi M. Purification of shikimie acid [ P]. JP2001026567, 2001.
8Oomori K,Suzuki T. Method of purifying shikimic acid[ P]. WO 0168891,2001.
9Sakamoto K, Shibayama K. Purification of shikimic acid [P]. JP'2001011013,2001.
10Shibayama K, Sakamoto K. Purification or shikimic acid and shikimic acid derivative[ P]. JP2000351750,2000.

中国临床医学

2002年第6期

内容加载中请稍等...