摘要
目的:评估磁共振多技术成像对判断心肌存活性的价值。材料和方法:冬眠心肌模型猪6只,于术前、术后2周及5周行MR多技术成像(包括:形态扫描、电影扫描、心肌灌注及心肌活性扫描),判断心肌缺血区及坏死区大小,与病理对照评价其诊断的准确性。结果:术后2周模型猪左室平均4.2±0.8个节段心肌缺血、平均0.5±0.8个节段心肌变性坏死;术后5周模型猪左室平均3.4±0.9个节段心肌缺血、平均0.3±0.4个节段心肌变性坏死;术后5周的病理提示左室平均3.3±0.5个节段缺血,0.2±0.4个节段坏死。结论:术后5周时左室心肌缺血及变性坏死的范围较2周时缩小,MR多技术成像对判断心肌存活性敏感,但轻度高估了心肌缺血及变性坏死的程度。
Purpose: To evaluate the value of multimodality MR imaging in assessment of myocardial viability. Materials and Methods: 6 model pigs of hibernating myocardium underwent multimodality MR imaging before and 2 weeks, 5 weeks after sugery. The multimodality MR imaging include: morphology scanning, cine MRI, myocardial perfusion and viability imaging. The results of MRI in myocardium ischemia and necrosis were compared with that of pathology. Results:MRI displayed 4.2 ± 0.8 segments of left ventricle myocardium ischemia, 0.5 ± 0.8 segments myocardium denaturation and necrosis in 2 weeks after surgery. MRI displayed 3.4 ±0.9 segments ischemia, 0.3 ± 0.4 segments denaturation and necrosis in 5 weeks after surgery. The pathology of 5 weeks after surgery confirmed 3.3± 0.5 segments ischemia and 0.2±0.4 segments necrosis.Conclusion: The area of ischemia, denaturation and necrosis in 5 weeks after surgery smaller than that of 2 weeks after surgery. Multimodality MR imaging has a high sensitivity in assessment of myocardial viability, but slightly overestimating the ischemia, denaturation and necrosis of myocardium.
出处
《中国医学计算机成像杂志》
CSCD
2002年第6期385-390,共6页
Chinese Computed Medical Imaging
