高脂血症患者肝素液封管浓度的研究

Effect study of blocking integrated catheters with heparin in hyperlipemic patients

目的 :比较高脂血症患者行套管针留置期间 3种浓度肝素液封管的再通效果 ,以选出适宜的浓度。方法 :将入选对象根据肝素液浓度 5 0U/ml、75U/ml、10 0U/ml分 3组 ,每组 2 0例 ,男女各 10例 ,每组对象接受一次同一浓度的封管实验。观察再通效果。结果 :① 5 0U/ml组与 75U/ml组肝素液封管后阻塞率差异具有统计学意义。② 75U/ml组阻塞率明显高于 5 0U/ml组 (P <0 .0 1)。③ 75U/ml组与 10 0U/ml组阻塞率差异无统计学意义 (P >0 .0 5 )。结论 :75U/ml组肝素液为高脂血症患者封管的适宜浓度。

Objective:To compare the re-pass effect of blocking integrated catheters with three different heparin solution, 50U/ml, 75U/mland 100U/ml, in hyperlipemic patients. Method: Blocked integrated catheters with different heparin solution, 50U/ml, 75U/mland 100U/ml, in three groups of hyperlipemic patients(each group included 10 males and 10 females). The re-pass effect of different heparin was evaluated. Result: ①The statistical significance was observed between Group 50U/ml and Group 75U/ml. ② The re-pass effect in Group 75U/ml was much better than the effect in Group 50U/ml (P<0.01). ③There was no statistical significance between Group 75U/ml and Group 100U/ml (P>0.05). Conclusion: 75U/ml was the suitable heparin concentration for blocking integrated catheters in hyperlipemic patients.