HPLC法测定银菊口服液中的马钱苷

Determination of the Content of Loganin in Yinju Oral Liquid by HPLC

目的:建立银菊口服液的含量测定标准。方法:采用高效液相色谱法对制剂中的马钱苷进行含量测定。结果:马钱苷的检测线性范围为0.06～0.96μg,r=0.9996;平均加样回收率为95.986%,RSD为1.67%。结论:所建质量标准准确、可靠,可用于银菊口服液的质量控制。

Objective:To establish the content determined standards for Yinju Oral Liquid.Methods:HPLC was ap- plied to determine the content of loganin in preparation.Results:The content of loganin showed a good linear relationship at a range of 0.06～0.96∝g(r=0.9996).The average recovery was 95.986%,RSD was 1.67%.Conclusion:The standard is accurate,reliable,and can be used for quality control of Yinlian oral Liquid.