支架内血栓形成的原因及防治

Cause and prevention of stent thrombosis

目的探讨经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)后支架内血栓发生的原因及防治策略。方法对支架内血栓形成的病例进行回顾性分析。结果近5年497例PCI术后4例出现支架内血栓;其中,1例PCI术后30 min即出现支架内血栓,经再次PCI和调整抗凝、抗血小板药物治疗方案,患者症状缓解,安全出院。结论支架内血栓形成是严重影响冠心病患者预后的PCI术后并发症。结合患者具体病情,选择更具个性化的治疗,可避免支架内血栓形成。

Objective Investigate the causes and prevention of stent thrombosis after percu-taneous coronary intervention ( PCI).Methods Retrospective analysis was made on the cases of stent thrombosis .Results In the last 5 years, there were 4 cases of stent thrombosis in 497 PCI ca-ses.Among them, one case of stent thrombosis happened within 30 min after PCI.After second PCI and anticoagulant and antiplatelet therapy , the patient safely discharged .Conclusion Stent throm-bosis is a serious postoperative complication of PCI in patients with coronary heart disease .Considering patient ’s specific conditions , personalized treatment can prevent stent thrombosis .