糖尿病患者药物治疗的个体化考虑

Drug treatment for diabetic patients needs considering individual characteristics

糖尿病是以血糖升高为主要表现的常见非传染性流行病,每个患者都有其自身的特点,因此指南基础上的个体化治疗是糖尿病长期控制达标的基石。作者介绍糖尿病患者的空腹、餐后高血糖或组合特点和血糖控制目标,以表格的形式概括降糖药物的基本特性和不同药物对空腹或餐后血糖的作用优劣。根据血糖升高特点和药物作用特性,更加合理地选用药物,尽可能在有效降糖的同时,使其不良反应最小化,实现个体化治疗。

Diabetes mellitus is a common non-infectious disease with hyperglycemic charac-teristics, but every patient has his feature .Individualized therapy based on guideline is a successful cornerstone for achiving treatment target in diabetes mellitus .In the review, the fasting, postprandial or combined hyperglycemia features are introduced firstly , then the important features of different drugs are mentioned by means of figure or table .Finally, based on the predicted HbA 1c target and patient ’s concrete manifestations , the drugs which matches the patient best are chosen for better effects and lesser adverse reaction .