肺癌患者化疗相关性便秘的肠道康复训练

Effect of intestinal rehabilitation training on chemotherapy-related constipation in patients with lung cancer

目的探讨肠道康复训练改善肺癌患者化疗相关性便秘的效果。方法选取化疗行5-HT3受体拮抗剂止吐发生便秘的172例肺癌患者,按照随机数字表法将其均分为观察组和对照组各86例。两组患者均采用一般护理措施,其中观察组在一般护理基础上给予肠道康复训练,对照组在一般护理基础上遵医嘱给予口服杜密克干预,两组干预时间均为7 d。比较两组便秘改善情况,以及两组患者干预前及干预7 d时的焦虑及便秘相关生活质量测评结果。结果观察组第一次排便时间、大便恢复正常形态时间显著短于对照组,3 d内排便次数及3～7 d排便次数显著多于对照组(P <0. 05,P <0. 01);干预7 d观察组焦虑及便秘相关生活质量得分显著低于对照组(均P <0. 05)。结论肠道康复训练能够显著改善肺癌患者化疗相关性便秘的情况及不良情绪,提高其生活质量。

Objective To investigate the effect of intestinal rehabilitation training on chemotherapy-related constipation in patients with lung cancer. Methods A total of 172 lung cancer patients on chemotherapy who were given 5-HT3 receptor antagonists as an-tiemetic and developing constipation were randomly divided into 2 groups,with 86 cases in each group. Routine nursing care was given to all the patients. Besides that,the control group was instructed to take Duphalac orally,while the intervention group was subjected to daily intestinal rehabilitation training. The intervention lasted 7 days. Changes in constipation,before and after anxiety levels and constipation-related quality of life in the 2 groups were compared. Results The time to first defecation,the time to pass normal shaped stool,in the intervention group were significant shorter than the controls;the former had more frequent defecation within 3 days,and within the 3 - 7 days range,than the latter ( P < 0. 05,P < 0. 01) . On the 7th day,anxiety levels and constipation-related quality of life in the intervention group were significant lower than the controls( P < 0. 05 for both) . Conclusion Intestinal rehabilitation training can significantly improve the condition of chemotherapyrelated constipation and bad mood in patients with lung can-cer,thus enhance their quality of life.