自拟咯血方治疗支气管扩张症临床观察

目的:探讨自拟咯血方治疗支气管扩张症的临床疗效。方法:将临床诊断符合纳入标准的58例且中医辨证为痰热壅肺型咯血患者,采用随机数字表法分为治疗及对照组,每组病患分别为29例,治疗组采用中药组方自拟咯血方+垂体后叶素+据药敏结果抗感染类药物治疗,对照组单独使用垂体后叶素+据药敏结果抗感染类药物进行治疗,治疗后评估两组患者临床疗效。分别在治疗第三天、第七天抽血复测血清高敏C反应蛋白数值,评测治疗效果;治疗前、治疗后第七天中医症候积分比较。结果:临床疗效比较,治疗组总有效率(94.7%)明显优于对照组(84.2%)的有效率;血清高敏C反应蛋白数值间两个时间切点比较,在第三天二者无统计学差异,第七天治疗组明显优于对照组。治疗前后两组中医症候积分比较,治疗组总积分明显优于对照组。结论:中药组方自拟咯血方对支气管扩张症中医辨证为痰热壅肺型咯血患者具有良好的临床的疗效,能够显著改善患者临床症状。

Objective:To study the clinicalefficacy of self-made hemoptysis formula treatment the clinical curative effect of Bronchiectasis disease. Methods: The clinical in 58 cases patients with diagnosis accord and the TCM syndrome was characterized by phlegm-heat obstructing lung type hemoptysis,using the random number table method were divided into treatment and control group, each group of patients, 29 cases respectively, the treatment group treatment using traditional Chinese medicine formula and Pituitrin and anti-infective drug according to the results of susceptibility test, the control group treatment using Pituitrin and anti-infective drug according to the results of usceptibility test, to evaluate the clinical efficacy of two groups of patients.The serum high-sensitivity C-reactive protein values were measured by blood sampling at third and seventh days after treatment, comparison symptom scores between the two groups before treatment and at seventh day after treatment. Results: Clinical efficacy comparison,total effective rate of the treatment group(94.7%) was better than that of the control group(84.2%). Comparison of serum high-sensitivity C-reactive protein between two timepoints,on the third days there was no statistical difference between the two groups, on the seventh day the treatment group was better than the control group. Comparison symptom scores between the two groups before and after treatment,the total score of the treatment group was better than the control group. Conclusion:The self-made hemoptysis formula has a good clinical effect on Bronchiectasis patients with TCM syndrome of phlegm-heat obstructing lung type hemoptysis,can significantly improve the clinical symptoms in patients with the disease.