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去势对成年雄性斑胸草雀LMAN神经元电生理特性的影响 被引量:1

Effect of Castration on Electrophysiological Properties of LMAN Neurons in Adult Male Zebra Finches
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摘要 以成年雄性斑胸草雀为研究对象,利用膜片钳技术观察去势前后LMAN(Lateral Magnocellular Nucleus of the Anterior Neostriatum)的电生理活动,进一步探究AFP通路与鸣曲的关系.去势后,LMAN神经元的膜时间常数变短,膜电阻减小,动作电位潜伏期缩短,动作电位后超极化幅值变低,同时动作电位发放频率变快.结果表明:去势后LMAN神经元兴奋性增强,使AFP通路更加活跃,去势引起的鸣曲不稳定可能是AFP通路活动增强所致. To explore the link between AFP and song of adult male zebra finches,the effect of castration on electrophysiological properties of their LMAN neurons was investigated.Patch-clamp recording was used to record the electrophysiological properties of LMAN neurons.Membrane time constant,evoked AP latency,AHP peak amplitude and input resistance were found to decrease after castration.These indicate that castration increases excitability of LMAN neuron and song plasticity.
作者 吴丽 李东风 WU Li;LI Dongfeng(School of Life Sciences,South China Normal University,Guangzhou 510631,China)
出处 《华南师范大学学报(自然科学版)》 CAS 北大核心 2019年第3期57-61,共5页 Journal of South China Normal University(Natural Science Edition)
基金 国家自然科学基金项目(31472002)
关键词 去势 LMAN神经元 电生理特性 成年雄性斑胸草雀 castration LMAN neurons electrophysiological properties adult male zebra finches
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