广州市儿童及青少年代谢综合征肥胖指标诊断界值的研究

Diagnosis boundary values of metabolic syndrome obesity index for Children and adolescents

目的:研究广州市6~18岁人群腰围(WC)、腰围身高比(WHtR)的分布特征,在心血管疾病(CVD)危险因素评估的基础上提出6~18岁人群WC和WHtR的适宜界值。方法:利用受试者工作特征曲线(ROC)法分析广州市15 000名6~18岁儿童及青少年身高、体质量、WC及其相关代谢指征数据(血压、空腹血糖、血脂),探索预测心血管疾病的WC和WHtR的最佳界值点。结果:当WC百分比达到P85时,WHtR达到0.48时,空腹血糖、血压、血脂等心血管危险因素检出率明显增高。结论:建议将中国儿童青少年WC的第85百分位值,WHtR 0.48作为预测儿童青少年心血管病危险因素增加的适宜界值。WC和WHtR作为相对简单的检查方法,能很好地预测心血管疾病,建议列入学生体检的常规测量项目。

Objective: To determine the distribution characteristics of waist circumference(WC), waist height ratio(WHtR) of 6–18 years olds in Guangzhou, and to put forward the WC and WHtR appropriate boundary values for 6–18 years olds on the basis of cardiovascular disease(CVD) risk factor assessment.Methods: We analyzed the height, weight, WC and its metabolic indication data(blood pressure, fasting blood glucose, and blood lipids) of 15 000 children in Guangzhou, aged 6–18, with the receiver-operating characteristic curve(ROC), and explored the best value point of WC and WHtR for the prediction of cardiovascular diseases.Results: When the WC percent reached P85, and WHtR reached 0.48, the cardiovascular risk factors of fasting blood-glucose, blood pressure, and blood fat were significantly higher.Conclusion: The 85 th percentile value of WC and 0.48 of WHtR are the appropriate boundary values in increasing the cardiovascular disease risk factors in Chinese children and teenagers. WC and WHtR as a relatively simple inspection method, can well predict cardiovascular diseases, and be used in the conventional measuring items among students.