胰腺血管活性肠肽瘤的外科诊治

Diagnosis and surgical treatment for pancreatic vasoactive intestine polypeptide tumor

目的:探讨胰腺血管活性肠肽瘤的诊断及外科处理措施。方法:对1990年1月至2011年7月中南大学湘雅医院收治的7例胰腺血管活性肠肽瘤临床资料进行回顾性分析。结果:根据肿瘤发生的部位和性质选择不同的手术方式,全部7例术后腹泻等症状逐渐缓解,均治愈,随访表明上述患者生存期长达3~6年。结论:胰腺血管活性肠肽瘤发病率低,易误诊,手术切除肿瘤是最有效的治疗方法,结合生长抑素、介入等有效治疗方法可提高患者生存质量,并能使患者长期生存。

Objective:To explore the diagnosis and surgical treatment for pancreatic vasoactive intestine polypeptide tumor(VIPoma).Methods:Clinical data of 7 patients with VIPoma from Xiangya Hospital,Central South University between January 1990 and July 2011 were collected and analyzed retrospectively.Results:The different operation modes were selected according to the location of VIPomas,and the postoperative symptoms of all 7 patients were gradually relieved and cured.The follow up showed that life spans of the above-mentioned patients were 3-6 years.Conclusion:The incidence of pancreatic VIPoma is low but it is easy to misdiagnose.The excision for the tumor is the most effective therapy.Combining with somatostatin,intervention and other effective strategies,the life quality of patients can be improved and long-term survival may be achieved.