颅内海绵状血管瘤伽玛刀治疗的疗效分析

Therapeutic effect of gamma knife on intracranial cavernous angioma

目的:评价伽玛刀治疗颅内海绵状血管瘤(cavernous angioma,CA)的疗效。方法:回顾性分析122例(病灶数134个)伽玛刀治疗后的颅内CA病例。结果:平均随访43个月,无患者死亡,1人再手术,83%癫痫患者症状改善或消失,44%的患者病灶体积缩小(59/134),病灶再出血者7例,年出血率1.6%,11.5%患者出现脑水肿(14/122),经治疗后均明显好转。结论:伽玛刀是治疗颅内CA的安全手段,对患者的癫痫症状改善较明显;海绵窦区CA建议首选伽玛刀治疗。

Objective: To evaluate the therapeutic effect of gamma knife on patients with intracranial cavernous angioma (CA). Methods: The medical records of 122 patients (134 lesions) who underwent radiosurgery were reviewed retrospectively. Results: hT e average follow-up period was 43 months. No patient died. One patient underwent CA resection. In patients with epilepsy, 83% patients showed alleviation of seizures. About 44% of the lesions shrank in size after treatment with gamma knife radiosurgery (59/134). Seven cases had hemorrhage again after radiosurgery, and the overall annual hemorrhage rate was 1.6%. Edema was found in 11.5% patients (14/122) and all patients showed improvement atf er treatment. Conclusion: Gamma knife is a safe treatment for CA, which could obviously improve the symptoms of epilepsy. Gamma knife radiosurgery is the if rst option for the treatment of cavernous sinus angiomas.