定量磁敏感图在中枢神经系统疾病中的应用进展

Advances in clinical application of quantitative susceptibility mapping in central nervous system

敏感加权成像是一种高分辨率、三维梯度回波、完全速度补偿的MR技术,它对磁化率不同的物质敏感,然而具有定量特点的重建敏感加权成像图,即定量磁敏感图(quantitative susceptibility mapping,QSM),在钙、铁含量、微出血、静脉内血氧含量的变化监测的应用价值具有革命性意义。本文仅就QSM的原理及其在中枢神经系统中的最新应用进展进行综述。

Susceptibility weighted imaging(SWI) is a magnetic resonance technology with a high resolution, three-dimensional gradient echo and fully velocity compensated sequence. It is also sensitive to substance with different magnetisability. Based on the quantitative reconstruction of SWI, quantitative susceptibility mapping(QSM) has been used in monitoring the change of intravenous iron, calcium, microbleeds and oxygen content. This article summarizes principle of QSM and the latest progress of QSM application in the diseases of central nervous system.