四肢软组织脂肪肉瘤的影像学表现和病理组织学特征

Histopathological and imaging features for soft tissue liposarcoma of extremities

目的:全面分析四肢软组织脂肪肉瘤的影像学表现及病理组织学特征,为临床诊断提供参考性建议。方法:选取青海大学附属医院2012年10月至2014年10月收治的原发性四肢软组织肉瘤患者9例,分别对其超声、CT与MRI影像学检查结果及术后病理组织检查情况进行回顾性分析。全面阐述该肿瘤形态、大小、边界等临床表现,并分析其影像学表现与病理组织学特征的相关性。结果:本组患者中病变位置为下肢者8例,其中分别包括左小腿、左大腿与右大腿;病变位置为上肢者1例,为右上臂部位。另外,1例患者病变组织内存在出血表现,1例患者病变组织内具有钙化与液化表现。CT检查主要表现为低密度影与线状分隔影;超声检查中可见不同强度的似脂肪回声;MRI检查中以T1短信号和T2长信号为特征。结论:MRI等影像学检查在四肢软组织脂肪肉瘤中具有良好的特征性表现,可发挥良好的疾病诊断作用。

Objective: To analyze the histopathological and imaging features for soft tissue liposarcoma ofextremities and to provide guide for clinical diagnosis.Methods: Nine patients with soft tissue liposarcoma ofextremities received treatment in Qinghai University Affiliated Hospital from October 2012 to October 2014. The imaging features ofCT and MRI as well as the histopathological features were retrospectively analyzed. The pat t ern, size and border oftumor were observed, and the correlation between the pathological features and the imaging features was analyzed.Results: Lower limb lesion was found in 8 patients, including the left lower leg, left and right thigh, respectively. One patient had right upper arm lesion, 1 case had bleeding, and 1 case displayed with calcification and liquefaction performance. The CT examination showed low density shadow and linear separated shadow. The ultrasound examination displayed different intensity fat-like echo.There was short signal intensity on T1 weighted imaging and long signal intensity on T2 weighted imaging in MRI.Conclusion: MRI and other imaging examinations show good performance in detecting the features ofsoft tissue liposarcoma ofextremities, which possess diagnostic value.