IABP在严重心功能不全患者中的疗效、预后及对血浆NT-proBNP浓度的影响

Influence of clinical curative effective、prognosis and NT-proBNP level in severe cardiac insufficiency patients with IABP

目的:评估IABP在心功能不全患者中的临床疗效、预后及其对血浆NT-proBNP浓度的影响。方法:58例有血流动力学不稳定或心源性休克的高危患者,40例进行IABP辅助治疗,18例为对照组行药物保守治疗,在治疗的过程中比较2组治疗前后的血流动力学、NT-proBNP变化及再住院率和死亡率。并进行统计学分析。结果:IABP组血流动力学更稳定,患者半年再住院率、死亡率明显低于对照组(P<0.05);在治疗过程中I-ABP组较对照组血浆NT-proBNP浓度下降幅度也更显著。结论:对于有血流动力学不稳定或心源性休克的高危患者,IABP的置入能安全、有效的改善血流动力学,改善血清生化指标,改善预后,从而为进一步治疗争取到足够的时间,以减少心血管不良事件。

Objective To evaluate the influence of clinical curative effective、prognosis and NT-proBNP level in heart failure patients with IABP. Methods 58 patients with hemodynamic instability or cardiogenic shock. 40 cases treated with IABP-assisted treatment as IABP group, 18 cases treated with drug conservative treatment as control group. Comparison of the 2 groups in the change of hemodynamic、NT-proBNP level, readmission for half a year and mortality rate before and after treatment, then statistical analysis. Results The IABP group of blood flow dynamics more stable, patients six months readmission rates, mortality was significantly lower than the control group (P<0.05);IABP in the course of treatment group than the control group, the plasma concentration of NT-proBNP decline more pronounced. Conclusion IABP placement can be safe, effective improve hemodynam-ics、serum biochemical indicators, prognosis, for blood flow mechanical instability or cardiac shock in high risk patients, so as to secure enough time for further treatment in order to reduce the adverse cardiovascular events.