CD147与进展型脑梗死的临床研究

Clinical research of CD147 with progressive cerebral infarction

目的:探讨CD147与脑梗死及其进展型之间的关系。方法:将脑梗塞患者分为进展型脑梗死组和非进展型脑梗死组,对两组第一次院时1d、3d、5d和7d血清CD147进行比较。结果:进展型脑梗死组和非进展型脑梗死组患者各时间点CD147均高于对照组。进展型脑梗死组和非进展型脑梗死组患者在入院后3d、5d和7d比较,有差异。进展型脑梗死组CD147高于非进展型脑梗死组患者。结论:CD147在脑梗塞患者表达升高,并可能成为进展型脑梗塞的检验预测靶点。

Objective To investigate the relationship between CD147 and progressive cerebral infarction. Meathods Cerebral infarction patients were divided into progressive cerebral infarction group and non-progres-sive cerebral infarction group. 1d, 3d, 5d and 7d of the serum CD147 compared. Results At each time patients of progressive cerebral infarction group and non-progressive cerebral infarction group of CD147 were higher. Pro-gressive cerebral infarction group and non-progressive cerebral infarction group after admission 3d, 5d and 7d compared differences. The Progressive cerebral infarction group CD147 higher than non-progressive cerebral in-farction group. Conclusion In patients with cerebral infarction, the expression of CD147 elevated , may become the test predicted targets of the progressive cerebral infarction.