肝内胆管细胞癌磁共振扩散加权成像与TACE术后碘油沉积对照研究

Controlled Study of the Relationship between the Magnetic Resonance Diffusion-weighted Imaging and Iodized Oil Deposition in PCC after TACE

目的:分析肝内周围型胆管细胞癌(PCC)MR扩散加权成像与经肝动脉化疗栓塞术TACE术后碘油沉积的关系。方法:收集经病理证实的接受MRI扩散加权成像检查及TACE治疗的周围型胆管细胞癌患者17例的影像学及临床资料。并收集肝细胞癌20例、肝转移瘤26例行TACE治疗的影像资料作为对比,对PCC术后碘油分布形态进行统计分析。并与术前DWI图像进行对照分析。结果:PCC与肝细胞癌、富血供转移瘤组比较有显著差异,PCC与少血供转移瘤组无明显差异;本组17例PCC中14例周边部于DWI图可见明显高信号,其中13例可见碘油沉积,表现为稀糙型和缺损型分布型态。余3例胆管细胞癌于DWI图表现为高低混杂信号者,肿瘤中心及周边部位均见少量碘油沉积。结论:PCC TACE术后碘化油沉积量少,DWI能从微观层面反映胆管细胞癌TACE术后碘油沉积的病理基础。

Objective To study the correlation of PCC iodixed oil deposition after TACE with the magnetic resonance diffusion-weighted imaging. Methods The image information of 63 cases with PCC,HCC and hepatic metastasis were retrospectively reviewed and studied,including 17 case of PCC with DWI. To made statistics for the shape of distribution of iodized oli,and made controlled study between the DWIand iodized oil deposition in PCC.Results There are significant deviation of iodized oil among PCC、HCC and Well-supplied metastatic tumor.Mann-Whitney U = 52. 000,P = 0. 000; the iodized oil deposition of PCC and less-supplied metastatic tumor was no significant difference. Mann-Whitney U = 103. 500,P = 0. 746. The edge of 14 cases of PCC have obvious high signal on DWI,13 case of them have iodized oil deposition on the edge. The 3 other case have a small amount of deposition in edge and center,and with high and low mixed signal on DWI. Conclusion The deposition of iodized oil of PCC is not dissatisfied.,DWI can reflect the pathological basis of deposition of iodized oil of PCC on microlevel.