对比异甘草酸镁与多烯磷脂酰胆碱治疗脂肪肝的临床疗效

Comparison of the clinical efficacy of isoglycyrrhizinate magnesium and polyene phosphatidylcholine in treatment of fatty liver

目的 :观察异甘草酸镁与多烯磷脂酰胆碱单独使用治疗脂肪肝的临床疗效对比。方法 :选取我单位2013年1月~2014年4月期间因患有脂肪肝被收治的患者76例。其中37例使用多烯磷脂酰胆碱进行治疗,作为对照组。39例使用异甘草酸镁进行治疗,作为观察组。对两组的治疗效果及实验室指标进行对比分析。结果 :观察组在治疗后显效的27例,有效的11例,总有效率为97.44%,对照组显效的17例,有效的13例,总有效率为81.08%,观察组的治疗总有效率明显高于对照组,差异具备统计学意义。观察组治疗1周后的肝功能指标明显低于对照组,观察组治疗3周后的肝功能指标明显低于对照组,差异具备统计学意义。结论 :异甘草酸镁治疗脂肪肝有很好的疗效,丰富了临床治疗的手段,应当在临床中普及使用。

Objective To observe and compare the clinical efficacy of the isoglycyrrhizinate magnesium and polyene phosphatidylcholine alone in treatment of fatty liver. Methods Selected 76 cases of suffering from fatty liver patients who were admitted during January 2013 to 2014 April in my unit. in which 37 cases were used polyene phosphatidylcholine for treatment,as the control group.39 cases of were used magnesium isoglycyrrhizinate for treatment, as the observation group. Comparative analysis of two groups of treatment and laboratory parameters. Results Isoglycyrrhizinate magnesium treatment of observation group after treatment, markedly effective was 27 cases, effective was 11 cases, total effective rate was 97.44%, 17 cases of markedly effective in the control group, effective was 13 cases, total effective rate was 81.08%, The total effective rate of treatment in observation group was significantly higher, there was statistically significant differences. Liver function of observed group after one week of treatment was significantly lower than the control group, the observation group of liver function after 3 weeks of therapy was significantly lower than the control group, there was statistically significant differences. Conclusion Isoglycyrrhizinate magnesium treatment of fatty liver has a good effect, which enriches the means of clinical treatment,it should be universal use in clinic.