超早期缺血性脑血管病应用CT灌注成像的临床价值

Clinical application value of CT perfusion imaging in the diagnoses of hyperacute ischemic cerebrovascular disease

目的 :探讨CT灌注成像在超早期缺血性脑血管病中的诊断价值。方法 :回顾性分析我院2013年1月到2014年7月应用CT灌注成像进行诊断的96例超早期缺血性脑血管病患者,将患者分为短暂性脑缺血发作(TIA)组和脑梗死组,分析两组的局部脑血流容积(CBV)、局部脑血流量(CBF)及达峰时间(TTP)。结果 :TIA组患侧的CBV、CBF较健侧轻度下降,但未达统计学水平,TTP明显下降,与健侧相比差异具有统计学意义。脑梗死组患侧CBV、CBF与TTP比TIA组下降更为明显,差异达统计学水平。结论 :CT灌注成像能准确鉴别诊断TIA和脑梗死,其诊断结果可为超早期缺血性脑血管病的治疗方案的选择提供影像学依据。

Objective To explore the application value of CT perfusion imaging in the diagnoses of hyperacute ischemic cerebrovascular disease. Methods 96 patients with hyperacute ischemic cerebrovascular disease who got medical treatment in our hospital from 2013 January to 2014 July were retrospectively analyzed, these patients were divided into TIA group and cerebral infarction group, the CBV, CBF and TTP of these two groups were compared. Results CBV and CBF of the affected side of TIA group decreased slightly, but did not reach significant level, TTP dropped markedly and had significant difference with unaffected side, CBV, CBF and TTP of the affected side of cerebral infarction group dropped more obvious than the affected side of TIA group, the difference reached significant leve. Conclusion CT perfusion imaging could discriminate TIA and cerebral infarction correctly, its diagnostic results are available valuable imaging basis of selecting therapeutic regimen for hyperacute ischemic cerebrovascular disease.