伴高脂血症的老年急性胰腺炎患者C反应蛋白的检测意义

The detective significance of CRP in acute pancreatitis gerontal patients with hyperlipemia

目的 :探析C反应蛋白(Crp)在伴高脂血症的老年急性胰腺炎(hlap)严重程度评估中的重要作用。方法：分析2010年4月~2015年4月在我院接受治疗的48例老年hlap患者的临床资料。根据老年hlap患者的严重程度将入选者分成map组(28例)和Sap组(18例)两组。比较两组患者的基线资料、胆固醇(Chol)、血清甘油三酯(Tg)和Crp以及治疗前后CT、ranSon、apaChe评分。结果 :两组患者在基线资料间的差异无统计学意义。Sap组的Crp及Tg水平均明显高于map组;两组患者的Chol无统计学差异。所有患者在接受2-3次的血液滤过和血脂吸附治疗后,用降脂药和强化胰岛素等进行辅助治疗,基本将血脂降至正常范围内,比较治疗前、治疗后的CT、ranSon、apaChe评分,发现有统计学差异。结论 :高脂血症(hl)是ap发病的一个危险因子;Crp的检测可以作为评估ap患者病情的严重程度的一个重要指标。

Objective Our retrospective study was aimed toanalyze the efficacy of CRP in severity assessment of geron-tal patients with hyperlipemic acute pancreatitis (HLAP).Methods Clinical data of 48 gerontal patients with HLAPreceived treatment at our hospitalfrom April, 2010 to April, 2015 was retrospectivelyanalyzed. Patients included were divided into two groups according to the severity assessment, MAP group (28 cases) and SAP group (18 cases). The general information, the levels of CHOL, TG, CRP and the values of CT, Ranson, APACHE scores before and after treatment of patients in two groups were compared. ResultsThe general information of patients in two group had no statistical difference. The levels of CRP and TG of patients in SAP group were obviously higher than those in MAP group. The level of CHOL of patients in two groups had no statistical difference. After the treatment of 2-3 times of blood filtration and blood lipid adsorption, adjuvant therapy with lipid lowering drugs and intensive insulin therapy, the values of CT, Ranson, APACHE scores before and after treatmentin two groups had statistical differences.Conclusion The hyperlipemia(HL) is a risk factor for the onset of AP. The detection of the level of CRP could be an important factor in assessing the severity of AP patients.