麝香乌龙丸联合云克治疗类风湿性关节炎效果观察

Effect of Shexiangwulong pill combined with Yunke in the treatment of rheumatoid arthritis

目的:探讨麝香乌龙丸联合云克治疗类风湿性关节炎效果观察。方法:将83例类风湿性关节炎患者分为两组,观察组采用麝香乌龙丸联合云克注射液治疗,对照组采用云克注射液治疗,对比两组患者治疗前后临床症状及生化指标变化情况。结果:观察组总有效率(95.24%)明显高于对照组(78.05%);两组治疗后肿胀指数、压痛指数、晨僵时间、类风湿关节炎活动度(DAS28)评分、休息痛均显著低于治疗前;观察组治疗后改善临床症状的程度显著优于对照组;两组治疗后血沉(ESR)、C反应蛋白(CRP)、类风湿因子(RF)、肿瘤坏死因子-α(TNF-α)、白介素1(IL-1)水平显著低于治疗前;观察组治疗后生化指标水平显著低于对照组治疗后。结论:麝香乌龙丸联合云克治疗类风湿性关节炎,能显著改善患者临床症状,减轻炎症反应。

Objective To investigate the effect of Shexiangwulong pill combined with Yunke in the treatment of rheumatoid arthritis. Methods 83 cases of patients with rheumatoid arthritis were divided into two groups. The observation group was treated with Shexiangwulong pill combined with Yunke injection. The control group was treated with Yunke injection. The changes of clinical symptoms and biochemical parameters were compared between the two groups before and after treatment. Results thetotal effective rate in the observation group(95.24%) was higher than that in the control group(78.05%). The difference was statistically significant. The two group after treatment, swelling index, tenderness index, morning stiffness, DAS28 score, rest pain were significantly lower than the level before the treatment. Difference was statistically significant. The improvement of clinical symptoms in observation group was significantly better than that in control group. The difference was statistically significant. Two groups after treatment CRP, RF, ESR, TNF-α, IL-1 levels were significantly lower than those before treatment. Difference was statistically significant. The level of biochemical markers in the observation group was significantly lower than that in the control group. The difference was statistically significant. Conclusion Shexiangwulong pill combined with Yunke in the treatment of rheumatoid arthritis can significantly improve the clinical symptoms and reduce the inflammatory reaction.