HbA1c、CK、FBG联合检测对糖尿病微血管病变的诊断价值

Diagnostic Value of Hb A1c, CK, FBG in the Diagnosis of Dabetic Microangiopathy

目的:研究检测糖化血红蛋白(HbA1c)、肌酸激酶(CK)和空腹血糖(FBG)对糖尿病微血管病变的诊断价值。方法:选择2012年1月~2015年1月我院糖尿病患者98例,按照有无发生糖尿病微血管病变分为无病变组36例,病变组62例,另选取同期在我院体检中心体检的60例健康者为对照组。比较各组的HbA1c、CK和FBG水平,并进行相关性分析。结果:糖尿病组的血清HbA1c、CK、FBG水平均明显高于对照组;病变组的血清HbA1c、CK、FBG水平均明显高于无病变组;经直线相关性分析,糖尿病微血管病变患者血清FBG水平与HbA1c水平呈正相关,与CK水平呈正相关,HbA1c水平与CK水平呈正相关。结论:HbA1c、CK、FBG是诊断糖尿病微血管病变的有效指标,三者联合检测对糖尿病微血管病变的诊断具有重要的临床应用价值。

Objective To study the diagnostic value of HbA1c, CK, FBG in diabetic microangiopathy. Methods Selected 80 patients with diabetic from Jan.2012 to Jan.2015, divided into two groups, selected 60 healthy persons as control group. The levels of HbA1c, CK, FBG were compared, and analyze the correlation. Results HbA1c, CK and FBG levels of diabetes group were significantly higher than control group; the serum levels of HbA1c, CK, FBG of pathological group were higher; FBG and HbA1c were positively correlated, CK were positively related, HbA1c and CK were positively correlated. Conclusion HbA1c, CK and FBG are effective indicators for diabetic microangiopathy, and has high clinical application value.