脑室腹腔分流联合颅骨缺损修补术治疗颅骨缺损合并脑积水的疗效及安全性分析

Efficacy and safety of ventriculoperitoneal shunt combined with skull defect repair in the treatment of skull defect with hydrocephalus

目的:分析脑室腹腔分流联合颅骨缺损修补术治疗颅骨缺损合并脑积水的疗效及安全性。方法:选取2011年12月~2016年12月期间在我院接受诊治的60例颅骨缺损合并脑积水患者作为研究对象,根据随机数表法分为对照组、研究组,各30例。对照组患者采用常规颅骨缺损修补术,研究组患者采用脑室腹腔分流联合颅骨缺损修补术治疗。观察并对比两组患者治疗后并发症、疗效及治疗前后神经功能情况。结果:研究组治疗后并发症总发生率13.33%(4/30)低于对照组的36.7%(11/30),差异有统计学意义;研究组患者治疗总有效率93.33%(28/30)高于对照组患者的70.00%(21/30),差异有统计学意义。治疗前,两组患者的神经功能NIHSS评分差异无统计学意义;治疗后两组患者神经功能NIHSS评分均低于治疗前,且研究组低于对照组,差异有统计学意义。结论:脑室腹腔分流联合颅骨缺损修补术可尽早的修补颅骨缺损合并脑积水患者颅脑缺损部位,安全性高,利于降低患者术后并发症发生率,减少神经功能损害,值得临床推广。

Objective To study the efficacy and safety of intraventricular cecal shunt combined with skull defect repair in the treatment of skull defects with hydrocephalus. Methods A total of 60 patients with skull defect and hydrocephalus who were treated in our hospital from December 2011 to December 2016 were selected as subjects. All the patients were divided into control group and study group according to the random number table method, 30 cases in each group. In the control group, the patients were divided into two groups: the intraventricular systolic shunt combined with the skull defect repair. The patients in the study group were treated with the same period of intraventricular systolic shunt combined with skull defect repair. To observe and compare the complications, curative effect and neurological function of the two groups before and after treatment. Results The total incidence of postoperative complications was 13.33%(4/30) in the study group compared with 36.7%(11/30) of the control group, the difference was statistically significant; The total effective rate was 93.33%(28/30) in the study group and 70.00%(21/30) in the control group, the difference was statistically significant. There was no significant difference in NIHSS score between the two groups before treatment. The NIHSS scores of neurological function were lower in the two groups than those before treatment, and the difference was statistically significant. Conclusion Intraventricular cecal shunt combined with skull defect repair surgery can repair skull defects as soon as possible with hydrocephalus in patients with craniocerebral defects, high security, help reduce the incidence of postoperative complications, reduce neurological impairment, worthy of clinical promotion.