GA、HbAlc、FBG的临床检测结果对妊娠结局的影响研究

Effect of clinical test results GA, HbAlc, FBG on pregnancy outcomes

目的:观察糖化血清白蛋白(GA)、糖化血红蛋白(HbAlc)和空腹血糖(FBG)在妊娠糖尿病中的应用及对妊娠结局的影响。方法:选取2014年2月~2016年5月医院诊治的妊娠糖尿病患者45例,设为观察组,选取同期入院健康产检孕妇45例,设为观察组。采用液态酶法测定糖化血清白蛋白水平,采用高压液相法测定糖化血红蛋白,采用葡萄糖氧化酶法测定空腹血糖,比较2组妊娠解决。结果:观察组孕妇糖化血清白蛋白(GA)、糖化血红蛋白(HbAlc)和空腹血糖(FBG)水平,显著高于对照组;观察组自然分娩率,显著低于对照组;观察组剖宫产率、早产率及晚期流产率;2组产妇产后出血率差异无统计学意义;观察组产妇妊娠高血压、泌尿系感染及胎膜早破发生率,显著高于对照组。结论:GA、HbAlc和FBG在妊娠糖尿病能动态了解产妇血糖动态,加强血糖控制能改善妊娠结局,降低母婴并发症。

Objective To observe the serum glycated albumin(GA), Application and glycosylated hemoglobin(HbAlc) and fasting blood glucose(FBG) in gestational diabetes on pregnancy outcome. Method February 2014-May 2016 45 patients to hospital for treatment of gestational diabetes, observation group, select the health check-ups for pregnant women admitted to hospital over the same period, 45 cases observation group. Using liquid enzymatic glycated serum albumin, glycated hemoglobin using high pressure liquid method, using glucose oxidase fasting blood glucose, two groups were compared pregnancy resolved. Result The observation group of pregnant women glycated serum albumin(GA), glycated hemoglobin(HbAlc) and fasting blood glucose(FBG) levels were significantly higher; natural birth rate of the observation group was significantly lower than the control group; the observation group cesarean section rate, the rate of preterm delivery and late miscarriage rate; 2 group of postpartum hemorrhage rate was no significant difference; observation group maternal gestational hypertension, urinary tract the incidence of infection and premature rupture of membranes, significantly higher. Conclusion GA, HbAlc and FBG in maternal gestational diabetes can dynamically learn glucose dynamics, strengthen blood glucose control can improve pregnancy outcomes, reduce infant and maternal complications.