动态增强磁共振成像、DWI及X线在诊断乳腺病变中应用价值比较

The application value of dynamic contrast enhanced magnetic resonance imaging, DWI and X-ray in the diagnosis of breast lesions

目的:比较分析动态增强磁共振成像(DCE-MRI)、弥散加权成像(DWI)、X线对乳腺病变的诊断价值。方法:100例乳腺病变(共126个病灶)患者均行X线、DCE-MRI、DWI检查,观察各自表现特点,并以病理结果为标准,比较分析三种不同检查方法对乳腺病变定性的诊断结果。结果:肿块形态、恶性钙化、大导管征等钼靶X线表现、DCE-MRI时间-信号曲线类型、表观扩散系数(ADC值)乳腺良恶性病变比较差异显著;以病理结果为标准,钼靶X线对乳腺恶性病变诊断灵敏度为69.12%,特异度68.97%,准确度69.05%,较DCE-MRI的86.76%、89.66%、88.09%,DWI的88.24%、94.83%、91.27%差异有统计学意义。结论:DCE-MRI、DWI对乳腺良恶性病变诊断价值类似,相比钼靶X线有明显优势。

Objective To compare and analyze the value of dynamic contrast-enhanced magnetic resonance imaging(DCEMRI), diffusion weighted imaging(DWI) and X-ray in the diagnosis of breast lesions. Methods A total of 100 patients with breast lesions(126 lesions) underwent X-ray, DCE-MRI and DWI examination, and the characteristics were observed. With the pathological results as the standard, the diagnostic results of the three methods were compared. Results The shape of tumor, malignant calcification, large ductal sign, DCE-MRI time-signal curve type, apparent diffusion coefficient(ADC value) showed no significant differences between benign and malignant breast lesions; With pathological results as the standard, the sensitivity, specificity and accuracy of mammography in the diagnosis of breast malignant lesions were 69.12%, 68.97% and 69.05%, respectively. Compared with those of DCE-MRI(86.76%, 89.66%, 88.09%) and DWI(88.24%, 94.83%, 91.27%), there were significant differences. Conclusion The value of DCE-MRI and DWI is similarin the diagnosis of benign and malignant breast lesions, and there are obvious advantages, compared with mammography.