自动咽鼓管吹张+球囊扩张术治疗鼻咽癌放疗患者分泌性中耳炎的研究

Study on treatment of secretory otitis media in patients with nasopharyngeal carcinoma treated by spontaneous eustachian tube blowout and balloon dilatation

目的 :探讨自动咽鼓管吹张+球囊扩张术治疗鼻咽癌放疗患者分泌性中耳炎的临床效果。方法 :选取2014年1月~2016年4月收治的80例患有分泌性中耳炎的鼻咽癌放疗患者展开研究。按照随机数表法,将入选对象随机分为对照组(42例)与观察组(38例)。对照组患者采用鼓膜置管术治疗,观察组患者采用自动咽鼓管吹张+球囊扩张术治疗。观察两组患者术后6个月的临床疗效,术后3个月、6个月、12个月的咽鼓管功能障碍评分和Valsalva测试评分,以及并发症发生率。结果 :观察组患者接受治疗后的临床有效率(94.74%)明显高于对照组(76.19%),比较的差异有统计学意义;两组患者术后3个月、6个月、12个月的ETQR-7评分均较治疗前有明显下降,观察组患者同期ETQR-7评分显著低于对照组;两组患者术后3个月、6个月、12个月的Valsalva评分低于术前,其中观察组同期Valsalva评分明显低于对照组;观察组患者接受治疗后的并发症率(7.89%)均明显低于对照组(42.86%),比较具有统计学意义。结论 :自动咽鼓管吹张+球囊扩张术治疗鼻咽癌放疗患者分泌性中耳炎具有显著的临床效果,可有效改善患者咽鼓管功能障碍以及临床症状,复发率低,安全性高,值得广泛在临床推广应用。

Objective To investigate the clinical effect of automatic eustachian tube blow + balloon dilatation in the treatment of secretory otitis media in patients with nasopharyngeal carcinoma radiotherapy. Methods 80 patients with nasopharyngeal carcinoma treated with secretory otitis media were enrolled from January 2014 to April 2016. According to the random number table method, the selected subjects were randomly divided into control group(42 cases) and observation group(38 cases). The patients in the control group were treated with tympanostomy. The patients in the observation group were treated with automatic eustachian tube bleed and balloon dilatation. The clinical efficacy of the two groups after 6 months of treatment, the 3-month, 6-month, 12-month Eustachian tube dysfunction score and the Valsalva test score, and the incidence of adverse events were observed. Results The clinical effective rate(94.74%) in the observation group was significantly higher than that in the control group(76.19%), the difference was statistically significant; Two groups of patients after 3 months, 6 months, 12 months were significantly lower than before treatment, the patients in the observation group had the same time ETQR-7 score were significantly lower than those in the control group; The Valsalva score was decreasing in the two groups at 3 months, 6 months, and 12 months, and the observation group was followed by the Valsalva score was significantly lower than that in the control group. The incidence of recurrence and the recurrence rate(7.89%) in the observation group were lower than those in the control group(42.86%), which was statistically significant. Conclusion The treatment of secretory otitis media in patients with nasopharyngeal carcinoma radiotherapy has significant clinical effect, which can effectively improve the Eustachian tube dysfunction and clinical symptoms, low recurrence rate, high safety and wide In clinical application.