脂脱搽剂配合梅花针及补肾养血胶囊治疗雄激素性脱发的临床观察

Clinical Observation on Androgenic Alopecia by Zhituo Liniment(脂脱搽剂),Plum-Blossom Needle and Bushen Yangxue Capsule(补肾养血胶囊)

目的:探讨脂脱搽剂配合梅花针及补肾养血胶囊治疗雄激素性脱发的临床疗效。方法:将120例雄激素性脱发患者随机分为治疗组和对照组各60例。治疗组患者采用脂脱搽剂配合梅花针及补肾养血胶囊治疗,对照组患者采用5%米诺地尔酊配合梅花针及补肾养血胶囊治疗。两组均治疗3个月。观察记录患者治疗前后中医证候积分;记录患者治疗后1个月、3个月脱发区头发生长情况。结果:总有效率治疗组为95.00%,对照组为78.33%;治疗组疗效优于对照组(P<0.05);治疗后,两组患者中医证候积分均降低(P<0.05);治疗后治疗组患者中医证候积分低于对照组,差异有统计学意义(P<0.05);治疗后1个月两组患者脱发区头发生长情况比较,差异无统计学意义(P>0.05);治疗3个月后,治疗组患者脱发区头发数量高于对照组,差异有统计学意义(P<0.05);对照组1例患者出现治疗区域轻度泛红,治疗组患者未见明显不良反应。结论:脂脱搽剂配合梅花针及补肾养血胶囊治疗雄激素性脱发有较好临床疗效,安全性良好。

Objective:To investigate the clinical effect of Zhituo liniment,plum-blossom needle and Bushen Yangxue capsule on androgenic alopecia.Methods:A total of 120 patients with androgenic alopecia were randomly divided into treatment and control groups,60 cases in each group.Patients were treated with Zhituo liniment,plum-blossom needle and Bushen Yangxue capsule in the treatment group.Patients were treated with 5%Minoxidil Tincture,plum-blossom needle and Bushen Yangxue capsule in control group.The two groups were treated for 3 months.The scores of TCM syndromes before and after treatment were recorded and the hair growth in the alopecia area was recorded at 1 st months and 3 rd months after treatment.Results:The total effective was 95.00%in treatment group and 78.33%in control group.The treatment group showed better efficacy than the control group(P<0.05).After the treatment,the scores of TCM syndromes were reduced in the two groups(P<0.05),and the treatment group showed lower TCM syndrome score than the control group(P<0.05).At the 1 st month after treatment,there was no significant difference in hair growth in hair area between the two groups(P>0.05).After 3 months of treatment,the treatment group showed more hair on the alopecia location than the control group,and the difference was statistically significant(P<0.05).In the control group,one case showed mild redness in the treatment area in one case,and there was no obvious adverse reaction in the treatment group.Conclusion:The application of Zhituo liniment,plum-blossom needle and Bushen Yangxue capsule showed good efficacy on androgenic alopecia,and the safety of drugs is good.