加味调气饮联合止痛灌肠汤治疗功能性肛门直肠疼痛

Jiawei Tiaoqi Drink Combined with Zhitong Guanchang Decoction in Treating Functional Anal Rectal Pain

目的:观察口服加味调气饮联合止痛灌肠汤治疗功能性肛门直肠疼痛的临床疗效。方法:100例功能性肛门直肠疼痛患者随机分为治疗组和对照组,每组各50例。治疗组给予口服加味调气饮联合止痛灌肠汤保留灌肠治疗,对照组给予止痛灌肠汤保留灌肠治疗。治疗14 d后,比较两组患者症状的改善情况、NRS评分、SF-36生存质量评分、焦虑及抑郁评分。结果:治疗组和对照组的有效率分别为94.00%、66.66%,两组有效率比较,差异有统计学意义(P<0.05)。两组治疗后NRS评分、SF-36生存质量评分、焦虑及抑郁评分均显著减低,且治疗组治疗后均低于对照组治疗后,差异均有统计学意义(P<0.05)。结论:加味调气饮联合止痛灌肠汤治疗功能性肛门直肠疼痛临床疗效显著,还可显著降低患者NRS评分、SF-36生存质量评分、焦虑及抑郁评分。

Objective:To observe the clinical efficacy of oral Jiawei Tiaoqi Drink combined with Zhitong Guangchang Decoction in treatment of functional anorectal pain.Methods:100 patients with functional anorectal pain were randomly divided into treatment group and control group,with 50 cases in each group.The treatment group was given oral Jiawei Tiaoqi Drink combined with Zhitong Guangchang Decoction in retention enema treatment,and the control group was given Zhitong Guangchang Decoction in retention enema treatment.After 14 days of treatment,the improvement of symptoms,NRS score,SF-36 quality of life score,anxiety and depression scores were compared between the two groups.RESULTS:The effective rates of the treatment group and the control group were 94.00%and 66.66%,respectively.The effective rate of the two groups was statistically significant(P<0.05).The NRS score,SF-36 quality of life score,anxiety and depression scores were significantly lower after treatment in both groups,and the difference was statistically significant after treatment in the treatment group(P<0.05).Conclusion:Jiawei Tiaoqi Decoction combined with Zhitong Enema Decoction is effective in the treatment of functional anorectal pain,and can significantly reduce the NRS score,SF-36 quality of life score,anxiety and depression score.