气管插管内给入维生素A预防和治疗BPD疗效观察

目的探究气管插管内给入维生素A在预防和治疗BPD方面的临床效果,方法选择2010年1月-2014年12月在我院NICU住院、需给予呼吸机支持治疗的患者,随机分为2组,治疗组60例,对照组60例。结果治疗组与对照组比较,疗效明显好于对照组(P<0.05);两组呼吸机治疗持续时间、氧疗持续时间及胸部X线提示有BPD改变时间比较,差异有统计学意义(P<0.05)。结论经气管插管内给入维生素A可以直接作用于呼吸道,增加生物利用率,对支气管肺发育不良起到有效预防及治疗作用,值得临床推广。

Objective To explore the clinical effect of A in prevention and treatment of BPD in patients with tracheal intubation.Methods 60 cases were randomly divided into 2 groups,60 cases in the control group,and cases in the control group.Results the treatment group compared with the control group,curative effect is obviously better than that of the control group(P<0.05);two groups of ventilator in the treatment of continuous time,oxygen therapy and continuous time and chest X-ray tips with BPD change time time difference was statistically significant(P<0.05).Conclusion intratracheal intubation into vitamin A can be directly in the respiratory tract,increased biological utilization rate of bronchial lung development adverse to effective preventive and therapeutic effect,is worthy of clinical promotion.