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BORIS蛋白表达水平对甲状腺癌病理资料及预后影响分析

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摘要 目的淘汰甲状腺癌中BORIS蛋白的表达水平及其与病理特征和预后的关系。方法采用免疫组化方法考察60例甲状腺癌组织和60例正常组织年BORIS蛋白的表达水平,比较不同病理特征和预后患者组织中BORIS蛋白表达差异。结果甲状腺癌组织中BORIS蛋白表达水平为83.3%,正常组织中BORIS蛋白表达水平为16,7%,甲状腺癌组织中BORIS蛋白表达水平显著高于正常组织(x^2=53.333,P<0.01)。BORIS蛋白在更高分级、未分化癌、高分期、转移以及生存期小鼠中表达率显著增加(P<0.05)。结论 BORIS蛋白在甲状腺癌的发生、发展中均有重要作用且以此影响了患者的预后。
出处 《环球中医药》 CAS 2015年第S2期244-244,共1页 Global Traditional Chinese Medicine
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参考文献11

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