超声造影和超声弹性成像联合诊断肝脏实性占位的价值探析

Analysis of Value of Contrast-enhanced Ultrasound Combined with Ultrasound Elastography in the Diagnosis of Solid Liver Space-occupying Lesions

目的探析超声造影和超声弹性成像联合诊断肝脏实性占位的临床应用价值。方法回顾性分析本院2017年5月-2018年5月我院确诊为肝脏实性占位疾病的1400例患者临床资料,患者均经手术病理学、超声造影及超声弹性成像检查,采用统计学方法分析超声造影和超声弹性成像联合诊断肝脏实性占位疾病的价值。结果本研究分析1400例患者临床资料,共检出肝实性占位病灶1498个,其中良性病变占46.19%(692个),恶性病变占53.81%(806个);超声造影示良性病灶697个,恶性病灶801个,超声弹性成像示良性病灶700个,恶性病灶798个,联合诊断示良性病灶703个,恶性病灶795个;联合诊断正确率、灵敏度、特异度、阳性预测值、阴性预测值分别为94.19%、94.51%、93.92%、93.03%、95.22%,超声造影诊断效能均明显高于超声造影(P<0.05),准确率、灵敏度及阴性预测值明显高于超声弹性成像(P<0.05)。结论超声造影和超声弹性成像联合检查有显著提高肝脏实性占位诊断效能,对良恶性病灶的鉴别诊断具有较高临床应用价值。

Objective To analyze the clinical application value of contrast-enhanced ultrasound combined with ultrasound elastography in the diagnosis of solid liver space-occupying lesions.Methods The clinical data of 1400 patients diagnosed as solid liver space-occupying lesions in our hospital from May 2017 to May 1818 were retrospectively analyzed.All patients were examined by surgical pathology,contrast-enhanced ultrasound and ultrasound elastography.The statistical method was used to analyze the value of contrast-enhanced ultrasound combined with ultrasound elastography in the diagnosis of solid liver space-occupying lesions.Results The clinical data of 1400 patients were analyzed,and a total of 1498 solid liver space-occupying lesions were detected,of which 46.19%(692)were benign lesions and 53.81%(806)were malignant lesions.Contrast-enhanced ultrasound showed 697 were benign lesions and 801 were malignant lesions,and ultrasound elastography showed 700 were benign lesions and 798 were malignant lesions,and the combined diagnosis showed 703 were benign lesions and 795 were malignant lesions.The accuracy,sensitivity,specificity,positive predictive value and negative predictive value of combined diagnosis were 94.19%,94.51%,93.92%,93.03%and 95.22%,respectively,and the diagnostic efficacy of contrast-enhanced ultrasound was significantly higher than that of ultrasound elastography(P<0.05),and the accuracy,sensitivity and negative predictive value were significantly higher than those of ultrasound elastography(P<0.05).Conclusion Contrast-enhanced ultrasound combined with ultrasound elastography can significant improve the diagnostic efficacy of solid liver space-occupying lesions,and has a high clinical application value in the differential diagnosis of benign and malignant lesions.