氯化锡催化合成苯甲酸乙酯的研究

Synthesis of EthylBenzoate Catalyzed by Stannic Chloride

以苯甲酸和无水乙醇为原料,采用氯化锡(SnCl4·5H2O)作催化剂合成苯甲酸乙酯,考察了催化剂用量、原料配比和反应时间等因素对反应产率的影响.确定了氯化锡作为催化剂的最佳反应条件:n苯甲酸∶n无水乙醇∶n氯化锡=1∶4∶0.01;反应温度为88℃;反应时间为60min;转化率(以苯甲酸计)可达93.5%.

Ethylbenzoate is synthesized from benzoic acid and anhydrous ethanol with stannic chloride( SnCl4·5H2O )as catalyst.The affection factors on the reaction such as proper amount of catalyst,material ratio and time of reaction have been studied.The best reaction condition as following∶hydroxybenzoic acid∶anhydrous ethanol∶stannic chloride=1∶4∶0.01(molar ratio);temperature of reaction:88 ℃;time of reaction:60 min.The yield of ethylbenzoate is 93.5% (based on benzoic acid).