蜈蚣藻化学成分研究

Study on chemical constituents of Grateloupia filicina

目的研究蜈蚣藻化学成分。方法用色谱和光谱技术分离并鉴定其化学成分。结果从蜈蚣藻中分离鉴定17个化合物,分别为:1,3-二羟基-2-甲氧基-5-羟甲基苯(1),N-甲基-L-酪氨酸(2),苯乙酰胺(3),黑麦草内酯(4),3-乙酰基苯甲酰胺(5),2-亚乙基-3-甲基琥珀酸(6),4-N甲酰胺基正丁酸(7),降倍半萜S-(+)-去氢催吐萝芙叶醇(8),鸟嘌呤核苷(9),马来酸(10),对羟基苯乙酰胺(11),6-氨基己酸乙酯(12),4-N甲酰胺基正丁酸甲酯(13),N-(2-羟乙基)-正己酰胺(14),麦角甾醇(15),4-氨基丁酸甲酯(16)和2,5-二叔丁基苯酚(17)。结论该17个化合物均为首次从该种蜈蚣藻中分离到。

Objective To study the chemical constituents of Grateloupia filicina.Methods The seventeen compounds were isolated and purified by chromatography methods.Their chemical structures were identified by physico chemical analysis.Results The compounds isolated fromGrateloupia filicina were identified as:3,5-dihydroxy-4-methoxybenzyl alcohol(1),N-methyl-L-tyrosine(2),benzeneacetamide(3),loliolide(4),3-acetyl-benzamide(5),2-ethylidene-3-methyl-butanedioic acid(6),4-[(aminocarbonyl)amino]-butanoic acid(7),3,5,5-trimethyl-4-hydroxy-4-(1-buten-3-one)cyclohex-2-en-1-one(8),guanosine(9),maleic acid(10),4-hydroxy-benzeneacetamid(11),6-aminohexanoic acid ethyl ester(12),butanoic acid,4-[(aminocarbonyl)amino]-methyl ester(13),N-(2-hydroxyethyl)hexanamide(14),ergosterol(15),4-aminobutanoic acid methyl ester(16),2,5-bis(1,1-dimethylethyi)phenol(17).Conclusion The 17 compounds were obtained from the Grateloupia filicinafor the first time.