红花黄色素氯化钠注射液联合酒石酸美托洛尔对不稳定型心绞痛患者心电图及血清MCP-1、MMP-9水平的影响被引量：4

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摘要目的探讨红花黄色素氯化钠注射液联合酒石酸美托洛尔对不稳定型心绞痛(UAP)患者心电图及血清单核细胞趋化蛋白-1(MCP-1)、基质金属蛋白酶-9(MMP-9)水平的影响。方法选取2017年1月—2018年8月河南圣德医院UAP患者100例,随机数字表法分组,各50例。对照组予以酒石酸美托洛尔,研究组予以酒石酸美托洛尔+红花黄色素氯化钠注射液,治疗时间为14 d。观察两组疗效,对比治疗前后心电图变化[12导联心电图ST段压低≥2.5 mm导联数(NST)、12导联ST段压低数值总和(ΣST)]、血清MCP-1及MMP-9水平。结果研究组治疗总有效率为96.00%,高于对照组76.00%(P<0.05);与对照组比较,治疗后研究组NST较少,ΣST较低(P<0.05);与对照组比较,治疗后研究组MCP-1、MMP-9水平较低(P<0.05)。结论 UAP采取红花黄色素氯化钠注射液与酒石酸美托洛尔联合治疗,可降低血清MCP-1、MMP-9水平,改善心电图,提高治疗效果。

作者周振

机构地区河南圣德医院心血管内科

出处《医药论坛杂志》 2019年第2期147-149,共3页 Journal of Medical Forum

关键词不稳定型心绞痛红花黄色素氯化钠注射液酒石酸美托洛尔 MCP-1 MMP-9

分类号 R541.4 [医药卫生—心血管疾病]

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