西酞普兰联合重复经颅磁刺激治疗抑郁症的临床疗效分析

Clinical analysis of citalopram combined with repeated transcranial magnetic stimulation in treatment of depression

目的分析对抑郁症患者采用西酞普兰、重复经颅磁刺激(rTMS)联合治疗疗效。方法随机将90例抑郁症患者划分为对照组、研究组,分别采用氢溴酸西酞普兰片治疗、氢溴酸西酞普兰片联合rTMS治疗,观察两组疗效。结果治疗后,研究组总有效率(97.78%)明显优于对照组(77.78%),研究组抑郁量表(HAMD评分)(12.3±2.6)分、不良反应(2.22%)均低于对照组(17.7±5.0)分、17.78%,有统计学意义(P<0.05)。结论氢溴酸西酞普兰片联合rTMS能有效改善患者抑郁症状,不良反应少,对抑郁症患者疗效突出。

Objective To analyze the efficacy of citalopram combined with repeated transcranial magnetic stimulation(rTMS)in the treatment of depression.Methods Totally 90 patients with depression were randomly divided into control group.The study group was treated with citalopram hydrobromide tablet,citalopram hydrobromide tablet combined with rTMS,and the curative effect was observed.Results After treatment,the total effective rate of the study group(97.78%)was significantly higher than that of the control group(77.78%).The scores of HAMD scale(12.3±2.6)and adverse reactions(2.22%)in the study group were lower than those in the control group(17.7±5.0),17.78%and there was statistical significance(P<0.05).Conclusion Citalopram hydrobromide combined with rTMS can effectively improve depressive symptoms with less adverse reactions.