宫内复苏术对足月胎儿窘迫脐血指标及新生儿神经功能的影响

Effect of intrauterine resuscitation on umbilical cord blood indexes of full-term fetal distress and neonatal nerve function

目的探讨对分娩且在产程中出现胎儿窘迫的产妇采用宫内复苏术治疗的临床效果。方法选择2016年3月—2018年6月在商丘市第一人民医院产科分娩且在产程中出现胎儿窘迫的60例产妇为研究对象,随机分为2组,各30例。对照组采用常规治疗,观察组采用宫内复苏术,比较两组脐血指标以及新生儿神经功能。结果观察组BE、PCO2绝对值低于对照组,PO2、HCO3-以及PH值绝对值高于对照组,差异有统计学意义(P<0.05);新生儿出生后各时间段,观察组S-100蛋白含量与NSE含量均明显低于对照组,差异有统计学意义(P<0.05)。结论宫内复苏术可有效调节足月胎儿窘迫脐血指标,利于缓解宫内缺氧情况,改善新生儿神经功能。

Objective To investigate the clinical effect of intrauterine resuscitation in treatment of fetal distress in pregnant women during delivery.Methods Totally 60 pregnant women with fetal distress during delivery in the department of obstetrics of Shangqiu the First People’s hospital from March 2016 to June 2018 were selected,and they were divided into two groups by random number table,with 30 cases in each group.Control group was given routine treatment,while observation group was given intrauterine resuscitation.The umbilical cord blood indexes and neonatal nerve function were compared between the two groups.Results The BE and PCO2 absolute value of observation group were lower than those of control group,while the PO2,HCO3-,PH absolute value were higher than control group(P<0.05);After birth of newborns at different time,the S-100 protein content and NSE content in observation group were lower than those in control group(P<0.05).Conclusion Intrauterine resuscitation can effectively regulate umbilical cord blood indexes of full-term fetal distress,relieve intrauterine hypoxia,improve neonatal nerve function.