早产儿支气管肺发育不良的防治进展

Progress inprevention and treatment for bronchopulmonary dysplasia in preterm infants

支气管肺发育不良是早产儿最常见的慢性肺部疾病,随着围产医学和新生儿医学的发展,极低出生体重儿和超低出生体重儿存活率明显增加,支气管肺发育不良发病率也有逐年上升的趋势。尤其是重度支气管肺发育不良更是极早早产儿死亡的主要原因之一。目前支气管肺发育不良的防治仍是研究的热点,糖皮质激素治疗支气管肺发育不良又有新的研究发展,应用具有广泛修复能力的干细胞治疗支气管肺发育不良的新方法很是值得期待。本文就支气管肺发育不良的防治进展作一综述。

Bronchopulmonary dysplasia isthe most common-chronic lung disease in preterm infants.With the development of perinatal medicine and neonatal medicine,the survival rate of very low birth weight infants and extremely low birth weight infants have increased significantly,but the incidence of bronchopulmonary dysplasia has been increasing year by year.In particular,severe bronchopulmonary dysplasia is one of the leading causes of death in earlier preterm infants.At present,the prevention and treatment of bronchopulmonary dysplasia is still a hot topic of research.New research progress has been made in the treatment of bronchopulmonary dysplasia with glucocorticoids.It is worthwhile to apply a new method for the treatment of bronchopulmonary dysplasia with stem cells with extensive repair ability.This article reviews the progress in prevention and treatment forbronchopulmonary dysplasia in preterm infants.