重症医学临床分离病原菌分布及耐药性研究

Study on Distribution and Drug Resistance of Clinical Isolates of Pathogenic Bacteria in Critical Care Medicine

目的研究重症医学临床分离病原菌分布及耐药性。方法该次研究对象选取2013年4月—2014年4月在该院重症监护病房中进行分离的病原菌的分布以及其耐药性进行探讨。结果研究结果表明,革兰阴性菌比例是5.00%,革兰阳性菌占35.00%,真菌占据10.00%,而这些菌种中比例最高的是革兰性阴性菌;铜绿假单胞菌对多黏菌素E敏感度先比显得较高;而鲍曼不动杆菌对亚胺培南、多黏菌素E的耐药率显得相对较低,差异有统计学的意义(P<0.05)。结论重症监护病房中比较常见的病原菌是革兰阴性杆菌,此类病原菌抗生素的耐药性非常严重,临床中应该不断提升对其耐药性的监测。

Objective To study on distribution and drug resistance of clinical isolates of pathogenic bacteria in critical care medicine. Methods The research objects selected from April 2013 to April 2014, pathogenic bacteria isolated from intensive care unit were studied on distribution and drug resistance. Results The results showed that the gram negative bacteria ratio was 5.00%,gram positive bacteria accounted for 35.00%, fungus occupied 10.00%, and highest proportion of these strains was gram negative bacteria; pseudomonas aeruginosa vs polymyxin E sensitivity ratio was higher; Acinetobacter baumannii vs Imipenem, polymyxin E resistance rate was relatively low, which was statistically significant(P<0.05). The results show that the proportion of Gram-negative bacteria is 5.00%, Gram-positive bacteria accounted for 35.00%, accounted for 10.00% of fungi, which is the highest proportion of species of gram-negative bacteria; Pseudomonas aeruginosa bacteria Polymyxa vitamin E higher than the sensitivity to appear; and Acinetobacter baumannii to imipenem resistance rate of polymyxin E is relatively low, there is statistical significance(P <0.05).Conclusion In the intensive care unit, the more common pathogenic bacteria was gram negative bacilli, the drug resistance of this kind of pathogenic bacteria was very serious and the monitoring of their drug resistance should be enhanced continuously.