埃索美拉唑联合木糖醇注射液治疗消化道出血疗效分析

Study on the Curative Effect of Esomeprazole Combined with Xylitol Infusion in the Treatment of Gastrointestinal Hemorrhage

目的分析消化道出血行埃索美拉唑与木糖醇注射液联合治疗的效果。方法回顾性分析2013年2月—2015年2月该院收治的消化道出血130例患者临床资料,按数字表法分为观察组和对照组,每组65例。对照组行西咪替丁治疗,观察组行埃索美拉唑与木糖醇注射液联合治疗,比较两组疗效。结果观察组总有效率96.92%显著比对照组70.77%高,且平均止血时间(1.50±0.02)d比对照组(3.65±2.36)d少,平均治疗时间(10.02±8.10)d比对照组(25.15±12.50)d少,比较差异均有统计学意义(P<0.05)。结论消化道出血患者行埃索美拉唑与木糖醇注射液联合治疗的效果显著,可有效止血。

Objective To analyze the effect of Esomeprazole combined Xylitol infusion in the treatment of gastrointestinal hemorrhage. Methods The clinical data of 130 patients with gastrointestinal hemorrhage treated in our hospital between February 2013 and February 2015 were reviewed, and were randomly divided into an observation group and a control group, each with 65 cases.Patients in the control group received Cimetidine for treatment, whereas those in the observation group were given Esomeprazole and Xylitol infusion combined for treatment. The curative effect was compared between the two groups. Results The total rate treatment effectiveness in the observation group was 96.92%, significantly higher than that in the control group, which was70.77%; And the mean time to hemostasis(1.50 ± 0.02) d d less than in the control group(3.65 ± 2.36), the mean duration of treatment(10.02 ± 8.10) d less than in the control group(25.15 ± 12.50) d, differences were statistically significant(P<0.05).Conclusion The combined therapy of Esomeprazole and Xylitol infusion is with significant curative effect for treating gastrointestinal bleeding, which can effectively stop the hemorrhage.