不同甲状腺激素水平及^(131)I剂量对甲状腺癌患者一次清甲成功率的影响研究

Different levels of thyroid hormone and ^(131)I dose on the success rate of a time Remove all thyroid cancer in patients

目的探讨不同甲状腺激素水平及131I剂量对甲状腺癌患者一次清甲成功率的影响研究,为进一步提高临床治疗效果提供新的资料和思路。方法回顾性分析该院于2011年1月—2014年12月收治的甲状腺癌患者69例,所有患者均在外科手术治疗后再行碘治疗,根据不同甲状腺激素水平及131I剂量对患者进行分组,分析不同分组间的一次清甲成功率。结果促甲状腺激素水平高于30μIU/m L和131I剂量高于3.7 GBq的甲状腺癌患者一次清甲成功率明显高(P<0.05),其中年龄、性别、碘摄取量病理分型等对一次清甲成功与否差异无统计学意义(P>0.05)。结论对于甲状腺癌术后患者,碘具有治疗难度低、副作用小、有效率较高等特点,可以在临床上推广使用。对于促甲状腺激素水平高于30μIU/m L临床效果更佳,131I剂量高于3.7 GBq临床效果满意。

Objective To investigate the different levels of thyroid hormone and131 I dose on the success rate of a time Remove all thyroid cancer in patients, provide new data and ideas in order to improve further clinical effect and cut down poison and side effect. Methods 69 patients with thyroid cancer who were treated in the hospital from December 2014 to January 2011 were retrospectively analyzed. All patients were treated with I after surgical treatment. The patients were divided into different groups accord-ing to different thyroid hormone levels and 131 I dose. Results The TSH level higher than 30 IU/m L and131 I doses higher than 3.7GBq thyroid cancer patients once a clear success rate were significantly higher(P<0.05), including age, gender, pathological type and iodine uptake on the time of a success was not significantly affected(P>0.05). Conclusion For the patients after thyroid carcinoma surgery, I had the characteristic that easy to treat, fewer side effect, higher efficiency, which is worthy of clinical populariza-tion. The clinical effect of thyroid stimulating hormone levels higher than 30 IU/m L is better, the clinical effect of 3.7 GBq higher than131 I doses is satisfactory.