奥曲肽不同应用方式治疗胰腺炎的临床效果分析

Analysis of the Clinical Effect of Octreotide in Different Application Methods of Treatment of Acute Pancreatitis

目的探讨不同方式的奥曲肽给药治疗胰腺炎的临床效果。方法整群选取该院收治的72例胰腺炎患者为研究对象,随机分成观察组和对照组两组,每组36例,对照组采取奥曲肽皮下注射治疗,观察组采取微量注射泵持续注射治疗,对比两组疗效。结果观察组患者治疗临床总有效率显著高于对照组(P<0.05),观察组临床症状消失时间、恢复进食时间、血淀粉酶恢复时间、住院时间显著短于对照组(P<0.05),不良反应总发生率低于对照组(P<0.05)。结论相较于奥曲肽皮下注射,微量注射泵持续注射的疗效更好,症状改善时间更短,缩短住院时间,不良反应发生率低,值得推广应用。

Objective To investigate the clinical effect of different ways of administration of octreotide in treatment of pancreatitis.Methods Our hospital 72 cases of acute pancreatitis in patients with as the research object and randomly divided into observation group and control group, each with 36 cases in each, subcutaneous injection of octreotide in treatment were adopted in the control group, observation group take micro injection pump for continuous injection in the treatment, compared two groups of curative effect. Results Patients in the observation group the clinical total efficiency was significantly higher than that of the control group(P <0.05) and observation group, the clinical symptoms disappeared time and eating recovery time, blood amylase recovery time,hospitalization time was significantly shorter than that in control group(P<0.05) and adverse reaction of total incidence rate lower than that of the controls(P<0.05). Conclusion Compared with subcutaneous octreotide and micro injection pump for continuous injection has better curative effect, improvement of symptoms in a shorter time, shorten the time of hospitalization, adverse reactions occur rate is low, it is worth popularization and application.