肺癌肿瘤标志物检验及其临床诊断分析

Tumor Markers of Lung Cancer and its Clinical Diagnosis Analysis

目的探讨肺癌肿瘤标志物检验及临床诊断价值。方法将整群选取该院2007年1月—2014年12月收治的肺癌患者98例设为肺癌组。将同期肺部良性肿瘤患者90例设为肺部良性肿瘤组;将排除肺部疾病90例体检者设为健康对照组。对比各组肺癌肿瘤标志物检验差异。结果肺癌组肿瘤标志物检出水平高于另两组(P<0.05)。肺腺癌组癌胚抗原、肺鳞癌组血清鳞状上皮细胞癌抗原,细胞角蛋白19片段检出水平、以及小细胞肺癌组神经特异性烯醇化酶检出水平均明显高于其他分组(P<0.05)。结论肿瘤标志物检验对肺癌诊断有参考价值,不同病理类型肿瘤标志物检出水平各有特点。

Objective To investigate the diagnostic value of tumor markers in lung cancer. Methods Choose our hospital in January 2007 ~2014 year 12 cases of lung cancer patients with lung cancer group 98. The lung cancer patients in the same period were 90 cases with benign lung tumors, and 90 cases with pulmonary disease were excluded. Difference of tumor markers in lung cancer. Results The detection level of tumor markers in lung cancer group was higher than that in other two groups(P<0.05). Lung adenocarcinoma cancer embryo antigen, lung squamous cell carcinoma group, the serum squamous epithelial cells cancer antigen,cytokeratin 19 fragment detection level, and small cell lung cancer group of nerve specific enolase detection level were significantly higher than those in the other group(P<0.05). Conclusion Tumor markers test for the diagnosis of lung cancer has a reference value, different pathological types of tumor markers detection level of each characteristic.