高压氧对重型颅脑损伤的疗效分析

Analysis of the Curative Effect of High Pressure Oxygen on Severe Cranio-cerebral Injury

目的临床应用高压氧治疗重型颅脑损伤并对其临床疗效进行分析。方法回顾分析在该院接受治疗的重型颅脑损伤的患者共1 060例的临床资料,其中2003年3月—2008年12月460例,作为对照组采用常规治疗方式;2009年1月—2014年6月600例,作为观察组在常规治疗方式的基础上另对患者实施高压氧治疗;对比两组临床疗效。结果观察组觉醒恢复时间短于对照组,P<0.05;治疗前两组GCS评分比较无差异,P>0.05;治疗后,观察组GCS评分与GOS评分显著高于对照组,P<0.05;观察组治疗有效率为96.17%,对照组治疗有效率为84.13%,明显观察组治疗效果更好,P<0.05。结论采用高压氧治疗重型颅脑损伤效果良好,临床应予以推广。

Objective To analyze the clinical efficacy of high pressure oxygen applied to the treatment of severe craniocerebral injury. Methods The clinical data about 1060 patients with severe craniocerebral injury treated in our hospital were reviewed. Of them, 460 cases admitted from March 2003 to December 2008 were treated by conventional therapy, and other 600 cases admitted from January 2009 to June 2014 were treated by high pressure oxygen and conventional therapy. And the clinical efficacy of the two groups was compared. Results The recovery time of the observation group was shorter than that of the control group, P <0.05. Before treatment, the difference in GCS between the two groups was not statistically significant, P>0.05. After treatment, GCS and GOS of the observation group was significantly higher than that of the control group, respectively, P <0.05. Compared with the control group, the observation group had much higher response rate(96.17% vs 84.13%), P <0.05. Conclusion High pressure oxygen has better effect on severe craniocerebral injury. It shall be promoted in clinical practice.