经颅二维及彩色多普勒超声在新生儿缺血缺氧性脑病中的应用研究

Application of Transcranial and Doppler Ultrasound in Neonatal Hypoxic Ischemic Encephalopathy

目的分析与探讨经颅二维及彩色多普勒在新生儿缺血缺氧性脑病(HIE)中的临床应用价值。方法整群选取该院于2013年3月—2014年2月间收治的缺血缺氧性脑病患儿93例为研究组,同期选取身体健康的正常足月儿93名为对照组,采用二维超声和彩色多普勒超声检查技术检测两组患儿在出生后48 h内的脑实质回声改变及血流动力学改变。结果在所有的HIE患儿中,中度各项指标分别为Vs(48.27±6.65)cm/s、Vm(28.20±5.37)cm/s、Vd(17.33±3.91)cm/s、RI(0.72±0.07)cm/s、PI(1.41±0.30)cm/s,重度分别为(43.45±5.70)cm/s、(27.01±3.57)cm/s、(15.43±2.83)cm/s、(0.85±0.12)cm/s、(1.43±0.18)cm/s,与研究组各项指标相比,差异具有统计学意义(P<0.05)。结论在临床中应用二维超声结合彩色多普勒检测新生儿HIE能及时反映二维形态及脑血流动力学改变,对HIE的准确检测和诊断有很重要的临床意义。

Objective To analyze the clinical application value of two dimensional and Doppler in neonatal hypoxic ischemic encephalopathy(HIE). Methods The hospital in hospital between March 2013 to February 2014 of hypoxic ischemic encephalopathy(HIE) 93 cases as study group. In the same time, select healthy normal full-term children 93 as control group, using two dimensional ultrasound and color Doppler ultrasound examination technique to detect the patients in two groups were within 48 hours after birth. Results In all of HIE, moderate indicators respectively vs(48.27±6.65) cm/s、Vm(28.20±5.37) cm/s、Vd(17.33±3.91)cm/s、RI(0.72±0.07)cm/s、PI(1.41±0.30)cm/s, severe(43.45±5.70)cm/s、(27.01±3.57)cm/s、(15.43 ±2.83)cm/s、(0.85 ±0.12)cm/s、(1.43 ±0.18)cm/s, compared with the indicators in the study group, the significant difference and was statistically significant(P<0.05). Conclusion In clinical the application of two-dimensional ultrasound combined with color Doppler flow imaging in diagnosis of neonatal HIE can reflect the two-dimensional shape and the change of cerebral hemodynamics and the accurate detection and diagnosis of HIE has very important clinical significance.