米索前列醇预防产后出血93例临床分析

Misoprostol in Preventing Postpartum Hemorrhage: An Clinical Analysis of 93 Cases

目的探讨米索前列醇预防产后出血的临床分析。方法整群选取2010年1月—2015年1月该医院收治的经阴道分娩伴产后出血高位因素186例产妇作为研究对象,按住院时间分为两组各93例,对照组给予缩宫素治疗,观察组给予米索前列醇治疗,比较两组产妇的2 h产后出血量和不良反应。结果观察组2 h产后出血量为(127.2±53.6)m L,对照组出血量为(289.6±71.3)m L,两组比较具有统计学意义(P<0.05),观察组不良反应发生率2.2%,对照组不良反应发生率4.3%,两组比较差异无统计学意义(P>0.05)。结论米索前列醇预防产后出血临床效果满意,值得应用。

Objective To investigate the clinical effect of misoprostol in preventing postpartum hemorrhage. Methods 186 pregnant women who were admitted to this hospital and underwent vaginal delivery complicated with high risk factors of postpartum hemorrhage were included in this study and divided into two groups with 93 in each one according to admission time. The control group was treated with oxytocin, while the observation group was treated with misoprostol. The 2h postpartum hemorrhage volume of the pregnant women and adverse reaction were compared between the two groups. Results The2 h postpartum hemorrhage volume was(127.2±53.6)m L in the observation group and(289.6±71.3)m L in the control group,and the difference was statistically significant, P <0.05. The adverse reaction rate was 2.2% in the observation group and4.3% in the control group, and the difference was statistically significant, P >0.05. Conclusion Misoprostol in preventing postpartum hemorrhage is worthy of application due to its satisfactory clinical effect.