替米沙坦采用不同给药时间用于高血压治疗的疗效分析

Observation on Efficacy of Telmisartan Administered at Different Times in Treatment of Hypertension

目的探究在高血压治疗中替米沙坦不同给药时间的治疗效果。方法整群选取该院在2013年3月—2015年3月期间收治的96例高血压患者,根据给药时间的不同将其分为对照组及观察组,两组患者均采用替米沙坦进行治疗,对照组在早晨给药,而观察组在晚间给药,对两组患者的治疗效果。结果经治疗,两组的疗效对比差异无统计学意义(P>0.05),而杓型高血压比例对比,观察组明显高于对照组,差异有统计学意义(P<0.05)。结论高血压治疗中替米沙坦具有较好的治疗效果,尤其在晚间给药效果更佳,在临床上值得推广应用。

Objective To explore the clinical effect of telmisartan administered at different times in the treatment of hypertension. Methods 96 patients with hypertension admitted to our hospital from April 2013 and April 2015 were divided into control group and observation group according to different administration time. All the patients were treated with telmisartan. The control group underwent morning administration while the observation underwent evening administration. The therapeutic effect was compared between patients of the two groups. Results After treatment, no statistically significant difference can be found in therapeutic effect between the two groups, P>0.05, but in terms of the proportion of dipper hypertension, the observation group was significantly higher than the control group with statistical difference, P <0.05. Conclusion Telmisartan in the treatment of hypertension has good therapeutic effect especially when it is administrated in the evening,and this method should be widely applied in clinical practice.