中医药在预防Miles术后下肢深静脉血栓形成的应用探析

Analysis of Application of Traditional Chinese Medicine in Prevention of Lower Extremities Deep Venous Thrombosis After Miles Operation

目的研究中医药预防Miles术后下肢深静脉血栓形成的临床效果。方法整群选取2011年5月—2014年4月来院行Miles术患者68例进行研究,按随机方法分为观察组(中医药治疗)与对照组(低分子肝素钙注射治疗)各34例,比较下肢深静脉血栓发生率与相关指标变化情况。结果 1与对照组相比,观察组的下肢深静脉血栓发生率(2.94%)以及D-D二聚体阳性率(5.88%)均有明显下降,组间对比差异有统计学意义(P<0.05);2治疗后观察组的血浆内皮素较对照组下降明显,差异有统计学意义(P<0.05)。结论中医药预防Miles术后下肢深静脉血栓的效果确切,可推广使用。

Objective To study the clinical efficacy of traditional Chinese medicine in prevention of lower extremities deep venous thrombosis after Miles operation. Methods 68 patients who underwent Miles surgery in this hospital between May2011 and April 2014 were included in this study and randomized to receive TCM therapy(the observation group, n=34) and injection of low-molecular-weight heparin calcium(the control group, n=34). The incidence of lower extremities deep venous thrombosis and the change of related indicators were compared between the two approaches. Results 1 The incidence of lower extremities deep venous thrombosis(2.94%)and the positive rate of D-dimer(5.88%)of the observation group were all lower than those of the control group, and the differences were statistically significant, P<0.05; 2 After treatment, plasma endothelin was obviously lower in the observation group than in the control group, and the difference was statistically significant, P <0.05. Conclusion The clinical efficacy of traditional Chinese medicine in prevention of lower extremities deep venous thrombosis after Miles operation is exact, and this method can be widely used.