血清生化指标改变对胆源性胰腺炎患者的鉴别诊断价值

The Serum Biochemical Indicators Change of Differential Diagnosis Value in Patients with Gallstone Pancreatitis

目的研究血清生化指标的改变鉴别诊断胆源性胰腺炎的临床价值。方法将整群选取的2013年5月—2015年5月期间该院诊断的88例胰腺炎患者分成胆源性胰腺炎组(48)和非胆源性胰腺炎组(40)。并检测其血清生化指标完成分析比较。结果胆源性胰腺炎患者感染分级、APACHEⅡ评分、ICU住院时间分别为(2.8±0.1)级、(11.4±2.1)、(4.1±0.5)d,与非胆源性胰腺炎患者相比,差异有统计学意义(P<0.05),胆源性胰腺炎患者r-GT(365.4±135.2)U/L、ALT(81.3±15.7)U/L、ALP(208.4±83.4)U/L、AST(72.7±34.2)U/L、DBIL(53.8±16.7)μmol/L、TBIL(105.6±36.7)μmol/L等血清生化指标均较非胆源性胰腺炎患者高,差异具有统计学意义(P<0.05)。结论血清生化指标中的r-GT、ALT、ALP、AST、DBIL及TBIL等指标检测对临床胆源性和非胆源性胰腺炎的鉴别诊断上有助于病情严重程度的早期鉴定。

Objective To study the changes of the serum biochemical indicators to identify the clinical value of diagnosis of gallstone pancreatitis. Methods 88 patients with acute pancreatitis from May, 2013 to May, 2015 were divided into group of gallstone pancreatitis(48) and non gallstone pancreatitis group(40). Complete analysis and detect the serum biochemical indicators. Results Biliary pancreatitis patients with infection grading, APACHE II score, length of hospitalization time were(2.8 ± 0.1),(11.4± 2.1),(4.1± 0.5 d), and non(P<0.05), the difference was statistically significant compared with patients with gallstone pancreatitis, r-GT patients with gallstone pancreatitis(365.4 ± 135.2) U/L, ALT(81.3 ± 15.7) U/L, ALP(208.4 ±83.4) U/L, AST(72.7±34.2) U/L, DBIL mu(53.8 ±16.7) mol/L, TBIL(105.6 ± 36.7) mu mol/L serum biochemical indexes such as the high patients with gallstone pancreatitis(P<0.05), statistically significant. Conclusion The serum biochemical indicators of r-GT, ALT, ALP, AST, TBIL and DBIL index detection for clinical gallstone and not on the differential diagnosis of gallstone pancreatitis is helpful to early identification of illness severity.