血必净注射液治疗慢性肾衰竭临床探讨

Clinical Observation on Xuebijing Injection in the Treatment of Chronic Renal Failure

目的探讨血必净对慢性肾衰竭的治疗效果。方法将随机选取的该院2009年5月—2014年11月门诊收治的80例慢性肾衰竭患者平均分为2组,其中对照组采用常规治疗,治疗组在对照组基础上加用血必净静点,疗程14d,观察治疗前后Bun及Scr变化情况。结果治疗组总有效率明显优于对照组(P<0.05),与治疗前相比,治疗组治疗后CCr明显上升(P<0.01),治疗前两组SCr无显著差异,治疗后。治疗组为(265.71±38.15)umol/L、对照组为(354.94±58.65)umol/L,差异具有统计学意义(P<0.01);治疗前两组BUN无显著差异,治疗后,治疗组为(16.65±3.88)umol/L,对照组为(23.45±6.28)umol/L,差异具有统计学意义(P<0.01)。结论血必净结合西医治疗治疗慢性肾衰竭,疗效显著。

Objective To investigate the therapeutic effect of xuebijing injection in treating chronic renal failure. Methods 80 patients admitted to outpatient department in our hospital between May 2009 and November 2014 were evenly divided into two groups. The control group was treated with conventional therapy, while the treatment group was given Xuebijing in-travenously additionally on the basis of conventional therapy for 14 d as one course. The changes of BUN and Scr before and after treatment were observed. Results The total effective rate of the treatment group was significantly superior to that of the control group, P<0.05; the CCr increased obviously in the treatment group after treatment compared with that before, P<0.01. No statistically significant difference can be found in SCr between the two groups before treatment, but after treat-ment, the SCr was(265.71±38.15)umol/L in the treatment group and (354.94±58.65)umol/L in the control group, and there was statistically significant difference between them, P<0.01; no statistically significant difference can be found in BUN be-tween the two groups before treatment, but after treatment, the BUN was (16.65±3.88)umol/L in the treatment group and(23.45±6.28)umol/L in the control group, and there was statistically significant difference between them, P<0.01. Conclusion Xuebijing injection combined with western medicine in the treatment of chronic renal failure has remarkable curative effect.