肝功能检测在胆囊结石有无合并无症状胆总管结石鉴别诊断中的意义

Significance of Liver Function Test in the Differential Diagnosis of Gallblad-der Stones Combined with Asymptomatic Common Bile Duct Stones

目的探讨肝功能检测在胆囊结石有无合并无症状胆总管结石鉴别诊断中的意义。方法随机选取2015年5月—2018年5月该院收治的胆囊结石患者213例,依据是否合并胆总管结石将这些患者分为两组,即单纯胆囊结石组(n=191)和胆囊结石合并胆总管结石组(n=22)。运用速率法检测ALT、AST、AKP、GGT、TBil、DBil水平。结果胆囊结石合并胆总管结石组患者的肝功能异常发生率77.27%(17/22)显著高于单纯胆囊结石组4.71%(9/191),差异有统计学意义(χ~2=12.83,P<0.05)。胆囊结石合并胆总管结石组患者的ALT、AST、DBil异常发生,68.18%(15/22)、68.18%(15/22)、68.18%(15/22)均显著高于单纯胆囊结石组3.66%(7/191)、3.66%(7/191)、4.19%(8/191),差异有统计学意义(χ~2=5.02,5.02,11.34,P<0.05)。结论肝功能检测特别是GGT检测在鉴别诊断胆囊结石有无合并无症状胆总管结石中具有较高的价值。

Objective To investigate the significance of liver function test in the differential diagnosis of gallbladder stones combined with asymptomatic common bile duct stones.Methods A total of 213 patients with gallstones admitted to our hospital from May 2015 to May 2018 were randomly selected.These patients were divided into two groups according to whether they had choledocholithiasis,ie,the simple gallstone group(n=191)and gallstones combined common bile duct stones group(n=22).The rate method was used to detect the levels of ALT,AST,AKP,GGT,TBil and DBil.Results The incidence of liver function abnormalities in patients with gallstones complicated with common bile duct stones was 77.27%(17/22),which was significantly higher than that in the simple gallstone group 4.71%(9/191),the difference was statistically significant(χ~2=12.83,P<0.05).ALT,AST,DBil abnormalities occurred in patients with gallstones complicated with common bile duct stones,68.18%(15/22),68.18%(15/22),and 68.18%(15/22)were significantly higher than 3.66%(7/191),3.66%(7/191),4.19%(8/191)in the simple gallstone group,the difference was statistically significant(χ~2=5.02,5.02,11.34,P<0.05).Conclusion Liver function test,especially GGT test,has a high value in the differential diagnosis of gallstones with or without asymptomatic common bile duct stones.